You MUST disconnect your internet or completely block Windows Update when running DDU until you have re-installed your new drivers
DDU should be used when having a problem uninstalling / installing a driver or when switching GPU brand
DDU should not be used every time you install a new driver unless you know what you are doing
DDU will not work on network drive. Please install in a local drive C:, D: or else
The tool can be used in Normal mode but for absolute stability when using DDU, Safemode is always the best
If you are using DDU in normal mode, Clean, reboot, clean again, reboot
Make a backup or a system restore but it should normally be pretty safe
It is best to exclude the DDU folder completely from any security software to avoid issues